15O-water

WHAT IS IT?

15O-water is a radioactive variation of regular water, in which the oxygen atom has been replaced by oxygen-15, a positron-emitting isotope.

QUALITIES

15O-water is metabolically inert and diffuses freely across the cell membrane and is therefore considered as the non-invasive gold standard for quantitative myocardial blood flow. It has a half-life of 122 seconds, which makes it possible to acquire multiple image scans in rapid sequence.

ARTICLES

MYOCARDIAL PERFUSION IMAGING WITH PET


This study measures the absolute myocardial blood flow using PET. It also discusses the characteristics of the radioactive tracers, that are available. It is shown that 15O-water is superior to the other tracers.

COMPARISON OF CORONARY CT ANGIOGRAPHY, SPECT, PET, AND HYBRID IMAGING FOR DIAGNOSIS ISCHEMIC HEART DISEASE DETERMINED BY FRACTIONAL FLOW RESERVE


This comparative study shows that positron emission tomography (PET), using 15O-water as a tracer, exhibit the highest accuracy for diagnosis of myocardial ischemia.

QUANTITATIVE ASSESSMENT OF MYOCARDIAL PERFUSION IN THE DETECTION OF SIGNIFICANT CORONARY ARTERY DISEASE


This study examines the cutoff values for absolute MBF and to evaluate the diagnostic accuracy of quantitative [15O]H2O positron emission tomography (PET). It concludes that the use of 15O-water in PET provides high diagnostic performance for quantitative MBF measurements.

MYOCARDIAL PERFUSION IMAGING WITH PET

COMPARISON OF CORONARY CT ANGIOGRAPHY, SPECT, PET, AND HYBRID IMAGING FOR DIAGNOSIS ISCHEMIC HEART DISEASE DETERMINED BY FRACTIONAL FLOW RESERVE

QUANTITATIVE ASSESSMENT OF MYOCARDIAL PERFUSION IN THE DETECTION OF SIGNIFICANT CORONARY ARTERY DISEASE


This study measures the absolute myocardial blood flow using PET. It also discusses the characteristics of the radioactive tracers, that are available. It is shown that 15O-water is superior to the other tracers.


This comparative study shows that positron emission tomography (PET), using 15O-water as a tracer, exhibit the highest accuracy for diagnosis of myocardial ischemia.


This study examines the cutoff values for absolute MBF and to evaluate the diagnostic accuracy of quantitative [15O]H2O positron emission tomography (PET). It concludes that the use of 15O-water in PET provides high diagnostic performance for quantitative MBF measurements.

Contact

+45 28 10 41 49 (GMT+1)
+1 (833) 615-4261 (USA)
connect@medtrace.dk

Social

Contact

+45 28 10 41 49 (GMT+1)
+1 (833) 615-4261 (USA)
connect@medtrace.dk

Social