aQuant is a software suite for the automated and robust analysis of 15O-water. The underlying algorithms of aQuant
have been used in more than 30 peer-reviewed studies over the last decade. aQuant is currently not approved by
the FDA, and is not CE-marked.
Results of MBF at stress and rest as well as Coronary Flow Reserve are presented as short and long axis images, polarmaps and in tabular form. Color coding helps the reader identify abnormal segments and defect size. Perfusable Tissue Index (PTI), a fibrosis index unique to 15O-water, is presented in a similar fashion. Build-in quality control helps the reviewer assess the quality of the scan.
Results are summarized on a report page and can be exported to local PACS system as a DICOM image. Parametric images can likewise be exported as DICOM images for documentation or subsequent fusion with CT angiogram.
Historically, the analysis of 15O-water was challenging due to high noise levels and low contrast. The introduction of PET/CT has greatly improved image quality, enabling a routine use of 15O-water. However, the low contrast remains, complicating analysis. Analyzing 15O-water therefore requires a different approach than normal: we first need to generate contrast.