From tumors and lung cancer to rib fractures and COVID-19 infiltrates.
Researchers at Aarhus University Hospital document that 15O-water PET myocardial perfusion imaging (MPI) often reveals several extracardiac findings or, in other words, findings outside of the intended scope. In their article recently published in Journal of Nuclear Cardiology they recommend that any 15O-water PET images revealing extra, and occasionally unexpected, findings are evaluated together with CT images when a patient is diagnosed.
The conclusions are based on 2963 patients scanned with 15O-water produced by MedTrace’s automated manufacturing system, P3 MT-100, at Aarhus University Hospital.
It is the first time that extracardiac findings using 15O-water PET are described and discussed, but it fits in line with the clinical experience from perfusion imaging with other PET tracers, the researchers write.
The article titled “Extracardiac findings with increased perfusion during clinical O-15-H2O PET/CT myocardial perfusion imaging: A case series” was published by:
Mads Ryø Jochumsen, MD, PhD (a,b), David Lyse Overgaard, MD (a),
Mikkel Holm Vendelbo, MD, PhD (a,c), Michael Alle Madsen, MD, PhD (a),
Lars Poulsen Tolbod, MSc, PhD (a,b), Lars Christian Gormsen, MD, PhD (a,b), and Trine Ørhøj Barkholt, MD, PhD (a)
Department of Nuclear Medicine and PET-Centre, Aarhus University Hospital, Aarhus N, Denmark (a)
Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark (b)
Department of Biomedicine, Aarhus University, Aarhus C, Denmark (c)
It provides clinically relevant information for colleagues at PET-centers who perform cardiac PET, and especially those who consider or plan to perform cardiac PET with 15O-water.