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The gold standard for quantifying blood flow is [O-15]-H2O
We are making it practically available for routine use

Higher Accuracy

Optimal kinetics allow application in most organs

Improved Efficiency

Higher patient throughput and in-house production

Better Safety

Lowest radiation exposure to patients and staff

OUR TECHNOLOGY


MedTrace develops a novel solution consisting of a hardware and analytical software solution which combined will revolutionize blood flow imaging in PET.

The software solution – aQuant – is a novel analytical platform under development to interpret the [O-15]-H2O PET scans. With the aQuant analysis software, MedTrace is developing the world’s first scanner independent, regulatory approved software offering absolute quantification. Compared to the early days of [O-15] – H2O research, aQuant offers clear visual interpretation along with absolute data.

The hardware part of the solution is the MT-100 (under development) that automates bedside production and infusion of [O-15]-H2O in the PET scanner suite – just in time for medical demands. The MT-100 will be the world’s first self shielded, GMP-compliant chemistry system for automated production and injection of [O-15] – H2O. End of Synthesis is >27 mCurie/ml.

The MedTrace solution is a platform technology. Our first priority is the heart study application (myocardial perfusion imaging), subsequently tumor and brain vascularization as well as diabetes studies.

“The flow of water through the tissues is essentially what makes life possible. All diseases affect the flow of water one way or another. This opens up powerful opportunities of diagnosis using [O-15] – H2O water and PET”

Professor Jens Soerensen MD PhD, PET Centre, Uppsala University Hospital, Sweden

CLINICAL BENEFITS


REVOLUTIONIZE BLOOD FLOW IMAGING IN PET

Currently, routine myocardial perfusion exams are performed with Tc-99m, Rb-82 and 13N-NH3. The globally recognized gold standard tracer for absolute blood flow measurements is [O-15]-H2O (radioactive water), which is used in many clinical studies as the benchmark. The short half-life of radioactive water, the difficult analysis as well as lack of regulatory approved equipment has limited its use in clinical practice so far. With MedTrace’s solution of hardware and analytical software, doctors all over the world will get clinical access to routine use of [O-15]-H2O.

THIS WILL ALLOW

Access to gold standard tracer ([O-15]-H2O) for routine blood flow exams
Faster patient turnaround (2-3 double-tests/hour)
Increased safety for patients and staff
In-house production of the tracer- no 3rd party logistics dependencies

Cardiology
Gold standard for myocardial perfusion

Oncology
Tumor microvasculature

Diabetes
Diabetic foot

Neurology  
Functional bloodflow – Apoplexy, Alzheimer’s

Clinical physiology
Organ blood supply

Tissue perfusion
Ischemic muscle, collateral blood supply

Oncology
Tumor microvasculature.
Neurology
Blood flow to selected brain domains, incl. quantification of apoplexy, alzheimer, dementia, schizophrenia etc.
Diabetes
Diabetec foot.
Cardiology
Myocardial perfusion – the gold standard.
Clinical Physiology
General organ specific blood perfusion, for organ functionality assessment.
Tissue perfusion
Ischemic muscle, collateral blood supply.

ABOUT MEDTRACE


OUR STORY

We are a development stage company innovating PET diagnostic imaging. Having experienced the challenges with false results in myocardial perfusion imaging, we are determined to make the perfusion tracer [O-15]-H2O (radioactive water) practically available for clinical use allowing doctors to use the gold standard in the clinic.

OUR PARTNERS

MedTrace collaborates with university hospitals in the US, Europe and Japan as well as global industry partners within nuclear medicine. We are continuously looking for interested clinical, technological and commercial partners globally.

“The availability of a reliable CE approved system for bed-side production of O-15 water could change O-15 water PET from an exotic research tool to a clinical workhorse”

Physicist Lars Poulsen Tolbod, Aarhus University Hospital, Denmark

OUR TEAM


Martin Stenfeldt

Martin Stenfeldt

CEO

Rune Wiik Kristensen

Rune Wiik Kristensen

Chief Operational Officer

Jens Soerensen, MD, Professor

Jens Soerensen, MD, Professor

Chief Medical Officer

Mark Lubberink, Professor

Mark Lubberink, Professor

Chief Scientific Officer

Peter Larsen, PhD

Peter Larsen, PhD

EVP, Hardware Development

Hans Harms, PhD

Hans Harms, PhD

VP, Software Development

Lars Poulsen Tolbod

Lars Poulsen Tolbod

VP New Indications

Pernille Randrup Vergmann

Pernille Randrup Vergmann

Design & Engineering Lead

 

Kasper Lykkegaard Therkelsen

Kasper Lykkegaard Therkelsen

Student Assistant - Usability and Engineering

 

Janine Sauer

Janine Sauer

Intern, Regulatory Affairs

Therese Eilskov Lundmark Jensen

Therese Eilskov Lundmark Jensen

Student Assistant – Legal Affairs

Naba Houssein

Naba Houssein

Student Assistant, Medical Affairs

OUR BOARD OF DIRECTORS


Ulrik Spork

Ulrik Spork

Chairman of the board, Medtrace A/S

Jens Soerensen, MD, Professor

Jens Soerensen, MD, Professor

Chief Medical Officer

Mads Rasmussen

Mads Rasmussen

Vice-chairman of the board, MedTrace A/S

Michael Frank

Michael Frank

Member of the board, MedTrace A/S

Bernt Skou Jensen

Bernt Skou Jensen

Member of the board, MedTrace A/S

OUR MENTORS


MedTrace participates in two team-mentoring groups; Scion Team Mentoring and NOME. MedTrace management meet regularly with the two mentor teams and received team-based feedback and coaching on operational and strategic topics.



OUR INVESTORS




GRANTS AND AWARDS


DTC Award

We are confident that the introduction of the MedTrace solution will be a paradigm shift in diagnostic imaging impacting most known disease areas.

Rune Wiik Kristensen, CSO, MedTrace A/S

REFERENCES


MEDIA

TECHNOLOGY

SCIENTIFIC


HQ
MedTrace A/S
Gotlandsvej 5
DK-5700 Svendborg

R&D
MedTrace A/S
Diplomvej 381
DK-2800 Lyngby

US Office
MedTrace Pharma, Inc.
545 Boylston Street
Boston, MA-02116

We believe that making [O-15]-H2O practically available for clinical use will change the world of perfusion exams.

Want to stay in contact and follow our journey? follow MedTrace on Facebook, LinkedIn, and Twitter.


+45 28 10 41 49 (GMT+1)
+1 (833) 615-4261 (USA)
connect@medtrace.dk
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